Let us create a 3D eBook for you!
Let us create a 3d Digital eBook for you! DigyCat.com

Policosinol and Cholesterol Reduction


The word cholesterol has become synonymous with poor health. Indeed, one does not typically hear the word used, or see it printed, unless it points to yet another distressing fact -- that high cholesterol is the number one factor for coronary heart disease, and the number one cause of heart attacks[i].

However, cholesterol is, in itself, not a negative thing. On the contrary, cholesterol plays a vital role in forming cell membranes, regulating hormones, insulating nerves, and more. The problem with cholesterol therefore lays not in cholesterol itself, but the amount of cholesterol present in the bloodstream. For most Americans who talk and read about this subject, the scenario almost always involves too much cholesterol, or the condition known as hypercholesterolemia.

When there is too much cholesterol in the blood, it cannot easily dissolve, and thus cannot effectively be transported to cells by the carrier called low-density lipoprotein (LDL). This can create a build-up of LDL cholesterol (a.k.a. "bad cholesterol"), and start to interfere with arteries that transport blood to the heart and brain. Both a stroke and a heart attack are the most severe manifestations of LDL cholesterol build-up, and the main reason why so many people are seeking ways to reduce the LDL build-up in their bloodstream[ii].

However, reducing cholesterol has been fraught with challenges. Though reducing or eliminating certain foods from diet is a necessary first step for most individuals, some who suffer from hypercholesterolemia require medical interventions to immediately begin lowering their risk of heart attack or stroke. As such, dozens of cholesterol-lowering statin drugs are currently on the market, and while some people have experienced relief due to their use, there are side effects that cause concern, including nausea, diarrhea, muscle tenderness, and increased liver enzymes[iii]. The out-of-pocket costs of these statin drugs can also be cost prohibitive for those not covered by a comprehensive drug plan.

However, a natural product called policosinol is generating an unusual amount of attention - both positive and negative - from the medical community in light of its purported cholesterol lowering capacity. Derived from the wax of sugarcanes and honeybees, policosinol is said by some to reduce cholesterol, offer no known side effects, be safe in high doses, increase blood flow, reduce platelet clumps, and prevent atherosclerosis (plaque buildup on the artery walls)[iv].

Studies have been conducted on policosinol efficacy, and there is some empirical research evidence that supports it as a high LDL cholesterol remedy. A 2002 study by researchers at the University of Bonn reviewed 60 clinical trials involving 3000 patients, and concluded with cautious optimism that policosinol is a promising alternative to cholesterol lowering stain drugs, and thus warrants further study[v].

However, those poised to buy policosinol and lower their cholesterol should approach with caution; and this is the message voiced by those who are less than enthusiastic about the policosinol's emergence as something of a wonder cure.

Though a natural remedy and thus far not causing the side effects associated with statin drugs, those skeptical about policosinol quickly point out that it is not an FDA approved drug. As such, it has not been subjected to the rigorous testing that comes with approving a new drug, including supervised preclinical trials and standardized testing in successively larger population of people. The fact that the FDA approves 1 out of 5000, or .0002 of the applications that it receives for new drug approval, is an indication of how highly valued - and rare - this approval is.

However, this instigates another debate - whether the FDA approval process is the most appropriate way to accept drugs into drug plans, and whether doctors should be permitted to prescribe non-FDA-approved drugs without undue concerns for malpractice lawsuits. Indeed, an MD may have personally benefited from a natural remedy like policosinol, but to prescribe that to a patient requires more support than personal preference, or even personal testimony.

And it is the intersection of these two separate debates -- whether policosinol works or not, and whether the FDA approval process is fair or not - that the situation, and verdict on policosinol, currently lies. This debate is frustrating to all sides; including patients themselves, who simply want a real solution.

However, despite these frustrations, the fact that efforts are being undertaken to develop - or verify - a remedy that is safe, complete, and free of side-effects - is a step in the right direction. Additional research on policosinol will further clarify whether that step should be towards FDA approval, or towards a warning label.

ABOUT PROTICA

Founded in 2001, Protica, Inc. is a nutritional research firm with offices in Lafayette Hill and Conshohocken, Pennsylvania. Protica manufactures capsulized foods, including Profect, a compact, hypoallergenic, ready-to-drink protein beverage containing zero carbohydrates and zero fat. Information on Protica is available at http://www.protica.com

You can also learn about Profect at http://www.profect.com

REFERENCES

[i] Source: "Heart Mender". CNN.Com. http://www.cnn.com/SPECIALS/2001/americasbest/science.medicine/pro.pridker.html

[ii] Source: "Cholesterol". American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4488

[iii] Source: "Statin Medications: What are the Side Effects?". Mayoclinic.com http://www.mayoclinic.com/invoke.cfm?id=AN00587

[iv] Source: "Policosinol ". Wholehealthmd.com. http://www.wholehealthmd.com/refshelf/substances_view/1,1525,10127,00.html

[v] Source: "Policosinol : clinical pharmacology and therapeutic significance of a new lipid-lowering agent". Gouni-Berthold I, Berthold HK. Am Heart J. 2002 Feb;143(2):356-65.

Copyright - Protica Research - http://www.protica.com


MORE RESOURCES:

Nutrition - Google News

This RSS feed URL is deprecated

This RSS feed URL is deprecated, please update. New URLs can be found in the footers at https://news.google.com/news

Thanksgiving Nutrition Tips: Eat Whatever You Want, but Not That - New York Times


New York Times

Thanksgiving Nutrition Tips: Eat Whatever You Want, but Not That
New York Times
It's Thanksgiving — a time for family, gratitude and historical revision of an indigenous genocide. Unfortunately for many Americans, Thanksgiving has become a time for overeating, followed by weight gain and inevitable self-loathing. But there's an ...

Quinn on Nutrition: Diabetes news - Circleville Herald


BenefitsPro

Quinn on Nutrition: Diabetes news
Circleville Herald
We got the historic news a little over a year ago … FDA's approval of an artificial pancreas for people with type 1 diabetes. These folks must needle-poke their fingers several times a day to determine if their blood sugar is too high or too low and ...
BWMC: Why diabetes is on the rise in young people CapitalGazette.com

all 27 news articles »

Enhanced Athlete Defeats Nutrition Distribution's Request for an ... - GlobeNewswire (press release)


Enhanced Athlete Defeats Nutrition Distribution's Request for an ...
GlobeNewswire (press release)
CHEYENNE, Wyo., Nov. 17, 2017 (GLOBE NEWSWIRE) -- Enhanced Athlete, a Cheyenne, Wyoming-based company focused on fitness and bodybuilding ...

and more »

Bean-to-bar chocolate makers in Delaware balance taste and - WHYY - WHYY


WHYY

Bean-to-bar chocolate makers in Delaware balance taste and - WHYY
WHYY
Mhairi and Stuart Craig are originally from Scotland, but today they call the arts and crafts community of Arden, Delaware home. Mhairi, a registered nurse, had ...

and more »

Scout and Zoe's Launches New Nutritional Treats Carpius Maximus ... - Business Wire (press release)


Business Wire (press release)

Scout and Zoe's Launches New Nutritional Treats Carpius Maximus ...
Business Wire (press release)
Scout & Zoe's launches Carpius Maximus, made of U.S. sourced carp to support local waterways. Treats are high in nutritional value for dogs and ca.

and more »

Nutrition is political and civil society needs to shape those politics ... - HuffPost


HuffPost

Nutrition is political and civil society needs to shape those politics ...
HuffPost
The two major nutrition meetings - the Global Nutrition Summit in Milan and the Scaling Up Nutrition Movement global gathering in Abidjan – held this mon...

and more »

WHO's Africa Nutrition Report highlights an increase in malnutrition in Africa. - World Health Organization


World Health Organization

WHO's Africa Nutrition Report highlights an increase in malnutrition in Africa.
World Health Organization
Abidjan, 16 November, 2017 - A newly released nutrition report by the World Health Organization (WHO) Regional Office for Africa has revealed that undernutrition is still persistent in the region and the number of stunted children has increased. The ...

Nestle reorganizes infant nutrition business - Reuters


Reuters

Nestle reorganizes infant nutrition business
Reuters
LONDON/ZURICH (Reuters) - Nestle (NESN.S), the world's largest packaged food firm, said on Wednesday it would reorganize its infant nutrition business to improve performance, five months after the new CEO listed the category as one of its priorities ...
Nestle restructures infant nutrition business Business Insider
Nestlé reorganizes infant nutrition business, announces changes to ... GlobeNewswire (press release)
Nestle Will Move Infant Nutrition Unit to Regionally Managed Business -- Update Fox Business
Financial Times
all 20 news articles »

9 Nutritionists Share the Worst Nutrition Advice They've Ever Heard - SELF


SELF

9 Nutritionists Share the Worst Nutrition Advice They've Ever Heard
SELF
There's a lot of really bad nutrition advice out there. I should know—I hear it every day, and so do my dietitian colleagues. Maybe we just notice it more, like someone who's phobic of something will be extra-attuned to the source of their phobia. At ...

LargeFriends.com - the best dating site for plus-sized singles!
SuccessfulMatchCentral.com - the best dating site for plus-sized singles!

PreLaunchX

DietRight.biz Domain Is For Sale - $8,500 For Enquiries eMail Us

© www.DietRight.biz 2012

home | site map | links